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TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 3
Descriptors Found:
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DeCS
Descriptor
English
:
Tumor Necrosis Factor alpha-Induced Protein 3
Descriptor
Spanish
:
Proteína 3 Inducida por el Factor de Necrosis Tumoral alfa
Descriptor
Portuguese
:
Proteína 3 Induzida por Fator de Necrose Tumoral alfa
Synonyms
English
:
TNFAIP3 Protein
Tumor Necrosis Factor alpha Induced Protein 3
Zinc Finger Protein A20
Tree Number:
D08.811.037.750.500
D08.811.277.656.300.887.750
D08.811.464.938.750.813
D12.644.360.950
D12.776.476.938
Definition
English
:
A
UBIQUITIN
editing enzyme that functions as both a
ubiquitin
ligase and deubiquitinase. It contains several
ZINC FINGERS
and functions in the immune response and
INFLAMMATION
by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via
TOLL-LIKE RECEPTORS
to terminate
NF-KAPPA B
activity.
History Note
English
:
2017
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56457
Unique Identifier:
D000072598
Occurrence in VHL
:
Similar:
DeCS